Neuromorphic Phototransistor with Biochemical Reconfigurability

Area of Science:

• Bioelectronics
• Neuromorphic Engineering
• Organic Electronics

Background:

• Current neuromorphic hardware relies on solid-state electronics, limiting biochemical interaction.
• Seamless human-robot interaction requires hardware with biochemical perception and reconfigurability.

Purpose of the Study:

• To develop a neuromorphic organic photoelectrochemical transistor (OPECT) with biochemical perception.
• To achieve bioswitchable signal transduction (excitatory/inhibitory) and dynamic reconfigurability.

Main Methods:

• Fabrication and characterization of a novel OPECT.
• Demonstration of biomolecule recognition and signal transduction.
• Construction of a closed-loop neuromorphic biosensing-feedback system.

Main Results:

• The OPECT exhibited bioswitchable positive and negative photoconductivity upon recognizing two different biomolecules.
• Dynamic conversion between excitatory and inhibitory behaviors was achieved by adjusting biomolecular ratios.
• A reconfigurable OPECT nerve successfully simulated chemical-mediated pupil dilation and contraction.

Conclusions:

• The developed OPECT offers a new platform for bioelectronic neuromorphic computing.
• This technology advances the potential for sophisticated human-robot interaction and bio-integrated systems.