Lesion Characteristics of Pulsed Field Ablation

Pulsed field ablation (PFA) has emerged as a promising, nonthermal technique for arrhythmia ablation, leveraging high-voltage electrical fields to induce electroporation and create precise ablation lesions. Unlike traditional thermal methods such as radiofrequency ablation (RFA) and cryoablation, PFA selectively targets myocardial cells while sparing surrounding tissues, reducing the risk of collateral damage. This review focuses on the key characteristics of PFA lesion formation, drawing comparisons with RFA and cryoablation based on histopathology, imaging, and electroanatomical mapping.