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Updated: Sep 20, 2025

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
[Long-term Outcome of Bypass Surgery for Moyamoya Disease]
Koji Yamaguchi1, Takakazu Kawamata
1Department of Neurosurgery, Tokyo Women's Medical University.
Abstract:
Moyamoya disease(MMD) is a progressive cerebrovascular disorder characterized by the stenosis or occlusion of the terminal portion of the internal carotid artery and its major branches. Surgical revascularization is important in the management of patients with MMD. This report compared the long-term outcomes of direct, indirect, and combined bypass techniques focusing on stroke recurrence rates and functional prognosis. Recent meta-analyses and clinical reports suggest that combined bypass provide the best long-term outcomes, reducing the risk of stroke recurrence and improving hemodynamic stability. These findings are crucial for neurosurgeons in selecting the optimal surgical approach for adult patients with MMD.
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