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Updated: Sep 19, 2025

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
A palladium-catalyzed borylative cyclization cascade reaction of 1,7-enynes: access to functionalized cyclohexanes
Weitian Qin1, Chengying Zhou1, Shaomin Fu1
1College of Chemistry, Sichuan University, Chengdu 610064, China. chembliu@scu.edu.cn.
Abstract:
This study describes a palladium-catalyzed borylative cyclization of 1,7-enynes, featuring mild reaction conditions, moderate to high yields (up to 87%), and excellent regioselectivity for synthesizing diverse functionalized cyclohexanes. The reaction exhibits good tolerance toward various substituents on both alkene and alkyne moieties-including internal alkenes and alkyne-bound aromatic groups, which were previously poorly compatible in related approaches-thereby highlighting the method's potential utility.
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