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A Quality Improvement Initiative to Optimize Early Mobilization in Acute Intracerebral Hemorrhage: A Pre-Post
Hsiao-Ching Yen1, Yun-Chen Tsai1, Guan-Shuo Pan1
1Division of Physical Therapy, Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei.
Neurorehabilitation
|June 9, 2025
Summary
A structured early mobilization protocol improved functional mobility in critically ill patients with primary intracerebral hemorrhage (ICH). This approach led to better outcomes and fewer adverse events during intensive care unit (ICU) stays.
Area of Science:
- Neurology
- Critical Care Medicine
- Rehabilitation
Background:
- Primary intracerebral hemorrhage (ICH) is associated with significant mortality and disability.
- Early mobilization is crucial for recovery but often delayed due to concerns about patient stability.
- Critically ill ICH patients require careful management to balance mobility benefits with safety.
Purpose of the Study:
- To assess the impact of a structured early mobilization protocol on functional mobility in critically ill ICH patients.
- To evaluate the effect of the protocol on the incidence of adverse events.
- To determine if early mobilization influences length of stay in the intensive care unit (ICU) and hospital.
Main Methods:
- Retrospective pre-post study design involving 192 patients with ICH (ICH score 0-4).
- Comparison of standard care (pre-implementation) versus a standardized mobility protocol (post-implementation).
- The protocol included time-based stratification, neurological thresholds, and safety criteria for activity progression.
Main Results:
- Patients in the post-implementation group achieved higher Modified ICU Mobility Scale (MIMS) scores at ICU discharge.
- A greater proportion of patients in the post-implementation group achieved out-of-bed sitting.
- Non-serious adverse events were significantly reduced in the post-implementation group.
Conclusions:
- A structured early mobilization pathway facilitates safer and earlier mobility in critically ill ICH patients.
- The protocol demonstrated improved functional outcomes within the ICU.
- While mobility benefits are evident, trends in length of stay require cautious interpretation due to non-significant findings.

