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Updated: Jun 12, 2025

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
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Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

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Cross-Reactive Carbohydrate Determinants (CCDs) Causing Interference in Allergen-Specific IgE Antibody Analysis

Jian-Qing Zhang, Hong-Gang Sun, Hong Chen

    Clinical Laboratory
    |June 11, 2025
    PubMed
    Summary

    Carbohydrate-deficient glycoprotein (CDG) specific IgE adsorbents accurately detect true allergen-specific IgE by removing interference. This improves diagnosis when test results conflict with clinical symptoms.

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