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Acute Poisonings, Suicidality and Systemic Inflammatory Load in Pregnant Women
Şenay Koçakoğlu1, Hasan Büyükaslan2
1Department of Family Medicine, Harran University Faculty of Medicine, Şanlıurfa, Türkiye.
Pregnancy increases the risk of intentional self-poisoning. While pregnant women show higher inflammatory markers (neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio), a direct link to suicidal tendencies requires further investigation.
Area of Science:
- Obstetrics and Gynecology
- Toxicology
- Emergency Medicine
Background:
- Pregnancy presents unique challenges and can elevate the risk of intentional self-poisoning.
- Understanding poisoning patterns and associated inflammatory responses during pregnancy is crucial for maternal health.
Purpose of the Study:
- To assess the incidence and clinical features of acute poisonings in pregnant women.
- To investigate the relationship between suicidal tendencies and systemic inflammatory load during pregnancy.
Main Methods:
- A 10-year retrospective study of 69 female patients (35 pregnant, 34 non-pregnant) with acute poisoning.
- Evaluation of sociodemographic data, clinical features, and routine blood results.
- Calculation of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) to quantify systemic inflammation.
Main Results:
- Intentional self-poisoning accounted for 85.71% of cases in pregnant women.
- Pregnant individuals exhibited significantly higher PLR and NLR compared to non-pregnant controls (P < .001).
- While NLR was higher in intentional poisonings and PLR in accidental ones, these differences were not statistically significant.
Conclusions:
- Acute poisonings in pregnant women are predominantly intentional.
- Elevated inflammatory markers (NLR, PLR) are observed in pregnant women, but a definitive link to suicidal tendencies was not established in this study.
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