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Updated: Sep 17, 2025

Preparation and Characterization of Lipophilic Doxorubicin Pro-drug Micelles
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Dynamic Dialysis Method for Characterizing Ammonia-Driven Drug Release from Liposomal Doxorubicin: Applicability and

Yoshinori Maeda1,2, Yuki Takechi-Haraya3, Emi Kawarai2

  • 1Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.

Chemical & Pharmaceutical Bulletin
|June 29, 2025
PubMed
Summary

The dynamic dialysis method (DDM) effectively measures liposomal doxorubicin release, confirming ammonia-driven release in tumor environments. This method provides a valuable framework for optimizing liposomal drug formulations.

Keywords:
drug releasedynamic dialysis methodkinetic analysisliposomal doxorubicinregulatory science

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