ASO Practice Guideline Series: Management of Colorectal Peritoneal Metastases

Area of Science:

• Oncology
• Surgical Oncology
• Gastroenterology

Background:

• Colorectal peritoneal metastases (CRPM) significantly impact quality of life and survival in colorectal cancer patients.
• CRPM pose a substantial challenge in clinical management.
• Effective treatment strategies are needed to improve outcomes.

Purpose of the Study:

• To review the current literature on the optimal management of CRPM.
• To identify areas of ongoing research in CRPM treatment.
• To provide guidance for clinicians managing patients with CRPM.

Main Methods:

• Systematic review of existing literature on CRPM management.
• Analysis of data regarding systemic chemotherapy and cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC).
• Evaluation of survival benefits and risks associated with different treatment modalities.

Main Results:

• Systemic chemotherapy is the standard treatment for metastatic colorectal cancer.
• CRS/HIPEC is an emerging option demonstrating survival benefits in selected CRPM patients.
• Identifying optimal management practices is critical due to the significant morbidity and mortality risks associated with CRS/HIPEC.

Conclusions:

• Optimal management strategies for CRPM are still evolving.
• Further research is needed to refine patient selection and treatment protocols for CRS/HIPEC.
• Guideline development is essential for standardizing care and improving patient outcomes in CRPM.