Related Experiment Video
Updated: Jul 15, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
MACULAR EXUDATION ASSOCIATED WITH A RACEMOSE HEMANGIOMA, VASOPROLIFERATIVE TUMOR, AND COATS-LIKE VASCULOPATHY
Gerardo Ledesma-Gil1, Martin A Mainster2, Carol L Shields3
1Retina Department, Institute of Ophthalmology, Fundación Conde de Valenciana, Mexico City, Mexico.
This study details a rare case of concurrent racemose hemangioma, retinal vasoproliferative tumor, and Coats-like vasculopathy. Combined laser photocoagulation and anti-VEGF therapy significantly improved vision in the affected eye.
Area of Science:
- Ophthalmology
- Retinal Vascular Diseases
- Medical Imaging
Background:
- Retinal vascular abnormalities can present with complex and overlapping features.
- Concurrent racemose hemangioma, vasoproliferative tumor, and Coats-like vasculopathy is exceptionally rare.
- Understanding the interplay of these conditions is crucial for effective management.
Purpose of the Study:
- To describe the clinical course and multimodal imaging findings.
- To document the outcome of treatment for a concurrent case of racemose hemangioma, retinal vasoproliferative tumor, and Coats-like vasculopathy.
Main Methods:
- Comprehensive ophthalmic examinations and multimodal imaging were performed.
- Treatment involved laser photocoagulation and intravitreal aflibercept injections.
- Follow-up extended for two years post-therapy.
Main Results:
- A 14-year-old male presented with severe visual impairment (20/400) due to macular exudation and multiple vascular anomalies.
- Treatment led to resolution of macular exudation and regression of the vasoproliferative tumor.
- Best-corrected visual acuity improved to 20/40 within two years.
Conclusions:
- The combination of rare retinal vascular abnormalities responded well to targeted treatment.
- Racemose hemangioma and abnormal hemodynamics may contribute to secondary vascular conditions.
- Effective management of exudation and proliferation can restore significant visual function.
More Related Videos
10:14Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
05:14Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
Published on: August 11, 2023
Related Concept Videos
Diabetic Retinopathy
Hemorrhagic Stroke ll: Pathophysiology
Cerebral Edema ll: Pathophysiology
Cytotoxic Edema: Pathophysiology