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Hypercalciuria: Diagnosis and Treatment
Vanessa A Lukas1, Daniel A Wollin1
1Department of Urology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Abstract:
Hypercalciuria is the most common biochemical predictor of calcium stones. It can be classified as absorptive (intestinal), renal, and resorptive (primary hyperparathyroidism), but most will be labeled as having idiopathic hypercalciuria. Assessment with serum laboratories and 24-hour urine collection is necessary for evaluation. A diet of low sodium, low animal protein, and adequate dietary calcium with fluid intake greater than 3.5 L/d is the mainstay of therapeutic intervention. Thiazides are an appropriate pharmaceutical adjunct in patients with persistent hypercalciuria and recurrent stones.
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