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4-Hy-droxy-N,N-diiso-propyl-tryptammonium hydro-fumarate
Marilyn Naeem1, Andrew R Chadeayne2, James A Golen1
1University of Massachusetts Dartmouth 285 Old Westport Road North Dartmouth MA 02747 USA.
Iucrdata
|July 9, 2025
Summary
The solid-state structure of a tryptammonium salt was determined. Hydrogen bonds between anions and cations form a complex three-dimensional network in the crystal structure.
Area of Science:
- Crystallography
- Solid-state chemistry
- Supramolecular chemistry
Background:
- Understanding the solid-state structure of organic salts is crucial for predicting their physical properties.
- Tryptammonium derivatives are of interest due to their potential biological and pharmaceutical applications.
Purpose of the Study:
- To report the crystal structure of a specific tryptammonium hydrofumarate salt.
- To analyze the intermolecular interactions, particularly hydrogen bonding, within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the atomic arrangement.
- Analysis of hydrogen bonding networks (O-H···O and N-H···O) was performed.
Main Results:
- The systematic name of the salt is [2-(4-hydroxy-1H-indol-3-yl)ethyl]bis-(propan-2-yl)azanium (2E)-3-carboxy-prop-2-enoate.
- Hydrofumarate anions form linear chains via O-H···O hydrogen bonds.
- These chains, along with tryptammonium cations, create a 3D network through O-H···O and N-H···O hydrogen bonds.
Conclusions:
- The study elucidates the intricate hydrogen bonding network governing the solid-state architecture of this tryptammonium salt.
- The findings contribute to the understanding of structure-property relationships in organic crystalline materials.
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