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Characterisation of the Novel HLA-C*14:168 Allele by Two Different Sequencing-Based Typing Techniques

Magali Devriese1,2, Anne-Flore Le Collonnier1, Melchior Le Mene1

  • 1Laboratoire d'Immunologie et Histocompatibilité, Hôpital Saint Louis, Paris, France.

HLA
|July 10, 2025
PubMed
Abstract

Keywords:
HLA‐CNGSnanotype sequencingsequencing‐based typing

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Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
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