[Specific growth rate and macrophagal infiltration of experimental tumors]

The relationship between the macrophage infiltration and the specific growth rate of tumours was studied by the technique of spontaneous migration of lymphoreticular cells from tissue fragments. In the case of dimethylnitrosamine-induced rat kidney tumours and Ehrlich solid tumour in mice the increased migration of activated macrophages was associated with the average specific growth rate. The macrophage infiltration of tumours and systemic immune reactivity to tumour-associated antigens depend probably on tumour cell kinetics.