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Endodontic Infections Requiring Hospitalization: Absolute Risk Estimations Based on Data From Two Swedish
Krister Sevä1, Thomas Kvist2, Fredrik Frisk3
1Department of Radiology, Sunderby Hospital, Sunderbyn, Sweden.
Journal of Endodontics
|July 18, 2025
Summary
Hospitalization for odontogenic infections is rare but more likely in smokers with mental health conditions and mandibular molar infections. The risk for hospitalization after root canal treatment is low.
Area of Science:
- Dental Public Health
- Infectious Diseases
- Epidemiology
Background:
- Limited understanding exists regarding oral conditions leading to odontogenic infections requiring hospitalization.
- This study investigates factors associated with hospitalization for odontogenic infections and quantifies hospitalization risks for specific endodontic conditions.
Purpose of the Study:
- To identify variables linked to hospitalization for odontogenic infections.
- To calculate the risk of hospitalization for various endodontic conditions.
Main Methods:
- A 9-year retrospective study of hospitalized patients for odontogenic infections in a Swedish region.
- Review of patient records and prior dental treatments, with statistical analysis and comparison to national data.
- Calculation of absolute risks for hospitalization due to endodontic conditions.
Main Results:
- 97 patients (mean age 47.03, 52% male) were included. Smokers and individuals with psychiatric diagnoses were more frequently hospitalized (P = .001).
- 80% of hospitalizations stemmed from mandibular molar infections, with 49.5% linked to endodontic infections.
- Absolute risk for primary apical periodontitis (AP) was 74.3/100,000 person-years; for secondary AP, it was 0.7/100,000 person-years. Hospitalization risk post-root canal treatment was 30/100,000 treatments.
Conclusions:
- Hospitalization for odontogenic infections is infrequent.
- Increased hospitalization risk is associated with mandibular molar infections, smoking, diagnosed mental health disorders, and delayed dental care seeking.
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