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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
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The Performance of ChatGPT-4.0 and ChatGPT-4omni on Answering Thyroid Question: A Multicenter Study
Siyin Guo1, Genpeng Li1, Juxiang Gou1
1Division of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
The Journal of Surgical Research
|July 24, 2025
Summary
ChatGPT-4omni demonstrated superior performance over ChatGPT-4.0 in answering thyroid health questions. This advanced AI shows promise for clinical integration, though further research is recommended.
Area of Science:
- Artificial Intelligence in Medicine
- Natural Language Processing
- Health Informatics
Background:
- ChatGPT-4.0 shows potential in medical applications.
- ChatGPT-4omni's efficacy in thyroid health inquiries remains unevaluated.
- This study assesses ChatGPT-4.0 and ChatGPT-4omni for thyroid health question response capabilities.
Purpose of the Study:
- To evaluate and compare the performance of ChatGPT-4.0 and ChatGPT-4omni in responding to thyroid-related patient questions.
- To assess AI-generated responses based on accuracy, comprehensiveness, empathy, and user satisfaction.
Main Methods:
- 30 thyroid-related questions (28 from Huayitong app, 2 interventional) were posed to ChatGPT-4.0 and ChatGPT-4omni.
- Responses were generated in Chinese on June 28, 2024.
- 60 patients, 29 surgeons, and 37 nurses rated responses on a 5-point Likert scale for various metrics.
Main Results:
- ChatGPT-4omni generated longer responses (750.50 vs 437.30 characters) and responded faster (20.68 vs 27.58 seconds).
- ChatGPT-4omni exhibited a higher response speed (34.26 vs 15.69 characters/second).
- Patients and healthcare professionals rated ChatGPT-4omni responses as more accurate, comprehensive, sympathetic, and satisfactory (P < 0.05).
Conclusions:
- ChatGPT-4omni significantly outperformed ChatGPT-4.0 in addressing common thyroid health queries.
- While promising, further research and optimization are necessary for effective clinical integration of AI chatbots.
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