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Updated: Sep 13, 2025

Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes
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Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes

Published on: September 12, 2018

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Selectivity Control in Visible-Light-Induced Three-Component Cascade Thiolation-Difluoroalkylation of Alkynes

Mengqi Zhu1, Huawen Huang1, Yun Wang1

  • 1College of Chemistry, Xiangtan University, Xiangtan, Hunan 411105, China.

Organic Letters
|July 30, 2025
PubMed
Summary

A new visible-light reaction enables regioselective thiolation-difluoroalkylation of alkynes. This method efficiently synthesizes gem-difluoroalkyl thioethers from diverse starting materials.

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