Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Bilateral retinal rescue through unilateral AAV8-CYP4V2 gene delivery in Bietti crystalline dystrophy.

Molecular therapy. Methods & clinical development·2025

Same author

Enhanced S-Cone Syndrome (Goldmann-Favre Syndrome).

Advances in experimental medicine and biology·2025

Same author

Inborn Errors of Metabolism: Bietti Crystalline Dystrophy.

Advances in experimental medicine and biology·2025

Same author

Prime Editing Strategy to Install the RPE65 c.1430A>G Dominant Mutation.

Advances in experimental medicine and biology·2025

Same author

De novo and inherited dominant variants in U4 and U6 snRNAs cause retinitis pigmentosa.

medRxiv : the preprint server for health sciences·2025

Same author

<i>In vivo</i> exchange of glucose and lactate between photoreceptors and the retinal pigment epithelium.

bioRxiv : the preprint server for biology·2025

Search research articles

Related Experiment Video

Updated: Sep 8, 2025

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Best Vitelliform Macular Dystrophy.

Laura A Jenny¹, Stephen H Tsang², Tarun Sharma¹

¹Department of Ophthalmology, Columbia University, New York, NY, USA.

Advances in Experimental Medicine and Biology

|July 30, 2025

Summary

This summary is machine-generated.

Best vitelliform macular dystrophy (BVMD) is a common inherited eye disease affecting 1 in 10,000 people. Its clinical presentation varies significantly across five distinct stages of disease progression.

Keywords:

Autosomal dominant Best disease

More Related Videos

Enrichment of Bruch's Membrane from Human Donor Eyes

Enrichment of Bruch's Membrane from Human Donor Eyes

Published on: November 15, 2015

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Related Experiment Videos

Last Updated: Sep 8, 2025

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Enrichment of Bruch's Membrane from Human Donor Eyes

Enrichment of Bruch's Membrane from Human Donor Eyes

Published on: November 15, 2015

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Area of Science:

Ophthalmology
Genetics
Retinal Diseases

Background:

Best vitelliform macular dystrophy (BVMD) is a prevalent inherited macular dystrophy.
It affects approximately 1 in 10,000 individuals worldwide.
Understanding its varied clinical presentation is crucial for diagnosis and management.

Purpose of the Study:

To describe the common clinical presentations of Best vitelliform macular dystrophy.
To outline the typical stages of disease progression.
To provide a comprehensive overview for clinicians and researchers.

Main Methods:

Review of clinical data from patients diagnosed with BVMD.
Analysis of ophthalmological examination findings.
Correlation of visual acuity and imaging results with disease stage.

Main Results:

BVMD exhibits a variable clinical course.
Five distinct stages of the disease are commonly observed.
Presentations range from asymptomatic to significant visual impairment.

Conclusions:

The clinical presentation of BVMD is highly variable.
Recognizing the five stages aids in patient management.
Further research into genotype-phenotype correlations is warranted.