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Cardiac Considerations in Pregnancy: A Spotlight on Peripartum Cardiomyopathy and Pregnancy-Associated Spontaneous

Sarah Thordsen1, Joan Briller2, Meredith O Cruz3

  • 1Division of Cardiovascular Medicine, University of Wisconsin Madison, Madison, WI 53792, USA.

Obstetrics and Gynecology Clinics of North America
|August 6, 2025
PubMed

Insights

Cardiovascular diseases during pregnancy, including peripartum cardiomyopathy (PPCM) and pregnancy-associated spontaneous coronary dissection (p-SCAD), are significant causes of maternal mortality. A multidisciplinary Cardio-Obstetric team approach is crucial for effective management.

Area of Science:

  • Cardiology
  • Obstetrics
  • Maternal-Fetal Medicine

Background:

  • Cardiovascular diseases are a leading cause of maternal morbidity and mortality.
  • The field of Cardio-Obstetrics addresses acquired, metabolic, and congenital heart conditions in pregnancy.
  • Peripartum cardiomyopathy (PPCM) and pregnancy-associated spontaneous coronary dissection (p-SCAD) are critical conditions specific to pregnancy.

Purpose of the Study:

  • To highlight the evolving landscape of Cardio-Obstetrics.
  • To emphasize the importance of recognizing and managing PPCM and p-SCAD.
  • To underscore the necessity of a collaborative team approach in managing cardiovascular complications of pregnancy.

Main Methods:

  • Review of current literature on Cardio-Obstetrics.
  • Analysis of the incidence and impact of PPCM and p-SCAD.
  • Discussion of the multidisciplinary team approach.

Main Results:

  • PPCM is a unique heart failure etiology in pregnant and postpartum women.
  • p-SCAD is the primary cause of acute myocardial infarction in this population.
  • Effective management necessitates expertise from various medical subspecialties.

Conclusions:

  • Cardiovascular complications significantly impact pregnancy outcomes.
  • Prompt evaluation of chest discomfort is vital.
  • A coordinated Cardio-Obstetric team is essential for optimal patient care and improved outcomes.

Keywords:
Acute myocardial infarctionCardio-obstetrics teamHeart failurePeripartum cardiomyopathyPregnancy-associated spontaneous coronary dissection

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