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Multidisciplinary Approach to Spinal Cord Stimulation for Persistent Spinal Pain Syndromes: A 65-Month Integrated
Lisa Bernaerts1,2, Ella Roelant3, Maarten Moens4
1Multidisciplinary Pain Center, Antwerp University Hospital (UZA), Edegem, Belgium.
Pain Research & Management
|August 12, 2025
Summary
Psychological factors predict spinal cord stimulation (SCS) success in neuropathic pain patients. Real-world data shows adherence declines, but battery life is consistent across SCS device types.
Area of Science:
- Neurology
- Pain Management
- Medical Technology
Background:
- Spinal cord stimulation (SCS) is a treatment for neuropathic pain.
- Long-term efficacy of SCS is debated, increasing the need for real-world data.
- A Belgian nationwide platform monitors SCS therapies since 2018.
Purpose of the Study:
- To update findings on SCS trial and long-term follow-up for persistent spinal pain syndrome.
- To analyze follow-up completion rates and implantable pulse generator (IPG) battery lifetime.
- To identify predictors of recovery and satisfaction in SCS patients.
Main Methods:
- Nationwide data extraction from the Belgian SCS monitoring platform (Neuro-Pain® registry).
- Analysis of patient data from a 3-week trial and long-term follow-up.
- Investigation of psychological variables ('yellow flags') and IPG battery performance.
Main Results:
- Psychological variables ('yellow flags') significantly predict SCS recovery and satisfaction.
- Patients completing follow-up showed better coping, lower anxiety, and improved functioning.
- Follow-up adherence decreased over time; no significant battery life difference between rechargeable and non-rechargeable IPGs.
Conclusions:
- Long-term neuromodulation outcomes are complex and multifactorial.
- The Neuro-Pain® registry aids in identifying predictors of SCS treatment success.
- Psychological factors are crucial for predicting SCS outcomes in neuropathic pain.

