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A Systematic Review of Health-Related Quality-of-Life Measurement in Patients With Complicated Intraabdominal
Abigail Rader1, Felicia Ruffin2, Caitlin Fai3
1Department of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Summary
Health-related quality-of-life (HRQoL) improves post-treatment for complicated intra-abdominal infections (cIAIs). Validated, disease-specific HRQoL measures are needed for patients with cIAIs, with the DV-QoL instrument as a potential model.
Area of Science:
- Medical research
- Health outcomes
- Quality of life assessment
Background:
- Complicated intra-abdominal infections (cIAIs) significantly impact patient health-related quality-of-life (HRQoL).
- Sepsis is a common complication associated with cIAIs.
- Understanding HRQoL is crucial for comprehensive patient care.
Purpose of the Study:
- To systematically review and assess health-related quality-of-life (HRQoL) measures used in patients with complicated intra-abdominal infections (cIAIs).
- To evaluate the impact of cIAIs on patient HRQoL.
- To identify gaps in current HRQoL assessment for cIAI patients.
Main Methods:
- Systematic review following a PROSPERO-registered protocol (CRD42021255827).
- Searched MEDLINE (PubMed), EMBASE, and CINAHL databases up to September 2022.
- Identified studies measuring HRQoL in patients with cIAIs.
Main Results:
- 93 articles were identified, utilizing 45 distinct HRQoL measures (32 generic, 5 condition-specific, 8 symptom-specific).
- Common symptoms impacting HRQoL included pain, fatigue, and incontinence; HRQoL generally improved post-treatment.
- Only the Diverticulitis Quality-of-Life (DV-QoL) instrument demonstrated psychometric testing in cIAI patients.
Conclusions:
- There is a significant need for rigorously tested and validated disease-specific HRQoL measures for cIAI patient populations.
- The DV-QoL instrument serves as a valuable reference for developing new, validated measures.
- Improved HRQoL assessment tools are essential for better management and outcomes in cIAI patients.
Keywords:
HRQOLcomplicated intraabdominal infectionpatient-reported outcomequality of lifesystematic reviewMore Related Videos
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