Related Experiment Video
Updated: Sep 11, 2025
06:02
Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
178
Transjugular Approach for Evoque Transcatheter Tricuspid Valve Replacement in Patients With Challenging Anatomy
Jonathan X Fang1,2, Pedro A Villablanca1, Tiberio M Frisoli1
1Center for Structural Heart Disease, Henry Ford Health System, Detroit, MI (J.X.F., P.A.V., T.M.F., L.K.L.L., J.C.L., P.E.G., B.Z., H.A., G.K.F., F.N., T.A., O.A., G.R., W.W.O.N., B.P.O.N.).
Circulation. Cardiovascular Interventions
|August 19, 2025
Summary
Transjugular Evoque transcatheter tricuspid valve replacement (TTVR) is feasible for patients with challenging anatomy unsuitable for transfemoral TTVR. This approach shows high success rates and favorable short-term outcomes, offering a viable alternative.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- The Evoque system is the first commercial transcatheter tricuspid valve replacement (TTVR) system in the US.
- Challenging patient anatomy can hinder successful transfemoral Evoque TTVR.
- The transjugular approach is explored for TTVR in anatomically complex cases.
Purpose of the Study:
- To investigate the feasibility of transjugular Evoque TTVR.
- To evaluate outcomes in patients with anatomy unsuitable for transfemoral TTVR.
Main Methods:
- Eleven patients with challenging anatomy underwent transjugular Evoque TTVR.
- Patients had either failed transfemoral attempts or were anatomically unsuitable.
- Outcomes assessed included procedural success, complications, echocardiography, and 30-day clinical events per TVARC definitions.
Main Results:
- 100% intraprocedural success was achieved in all 11 patients.
- No major procedural complications occurred, besides one pacemaker implantation.
- At 30 days, 100% clinical success was observed, with significant reduction in tricuspid regurgitation and improved NYHA functional class in most patients.
Conclusions:
- Transjugular Evoque TTVR is a feasible alternative for patients with challenging anatomy.
- The procedure demonstrated favorable short-term clinical and periprocedural outcomes.
- This approach expands TTVR applicability in complex cases.
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