Related Experiment Video
Updated: Sep 9, 2025

Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function
Published on: April 26, 2024
Recent Advances, Challenges, and Functional Applications of Protein Chemical Modification in the Food Industry
Peiming Zhao1, Zhiyan Zhang1, Wei Ran2
1Meat Processing Key Laboratory of Sichuan Province, College of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.
Protein chemical modifications enhance food properties like texture and stability. Artificial intelligence accelerates the discovery of new protein functions for food, medicine, and biomaterials.
Area of Science:
- Food Science
- Biochemistry
- Materials Science
Background:
- Proteins are vital in food processing, influencing texture and stability through their physicochemical properties.
- Protein functionality (emulsification, foaming, gelation, hydration) is determined by molecular structure.
- Protein modification techniques are used to enhance and diversify biological functions.
Purpose of the Study:
- To review chemical modification methods for improving protein functionality.
- To explore the role of artificial intelligence (AI) in protein modification research.
- To highlight the expanded applications of modified proteins in food, medicine, and biomaterials.
Main Methods:
- Review of chemical modification strategies for proteins.
- Integration of AI techniques (deep learning, image recognition, NLP) for predicting modification sites.
- Analysis of AI's role in rational protein design and engineering.
Main Results:
- Chemical modifications improve protein solubility, emulsification, gelation, antioxidant and antimicrobial activities, and nutritional value.
- AI technologies offer innovative tools for intelligent prediction of protein modification sites.
- Modified proteins show enhanced performance in food systems.
Conclusions:
- Protein chemical modifications are key to improving food product quality and expanding protein applications.
- AI is revolutionizing protein engineering by enabling targeted functional design.
- Modified proteins hold significant promise for advancements in food, medicine, and biomaterials.
Related Concept Videos
Protein Modifications in the RER
Broadly, these modifications can be categorized into four main categories — glycosylation, formation of disulfide bonds, assembly of protein subunits, and specific proteolytic cleavages like removal of signal...
Recombinant DNA
Protein Glycosylation
Glycosylation occurs in...
Protein-protein Interfaces
Covalently Linked Protein Regulators
These groups modify specific amino acids in a protein....
Bacterial Protein Maturation

