Related Experiment Video
Updated: Sep 9, 2025

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
Lifestyle Interventions in Frailty
Fernando Millan-Domingo1, Jose Viña2
1Department of Physiology, Faculty of Medicine, University of Valencia, Valencia, Spain.
Abstract:
Frailty is a major concern in gerontology and geriatrics as it may lead to disability. At the time of writing this review, 30% of the population over 65 in Europe (an in other parts of the world) are dependent on the care of other persons. It is estimated that this percentage may grow to 50% by 2050.A note of hope is that frailty (unlike aging itself) can be prevented and even reverted. Here we have reviewed two of the major lifestyle changes that are useful to treat age-associated frailty: nutrition and physical exercise. A common characteristic of both interventions is that they must be personalized. Precision interventions are now quite common in areas like oncology. A major evolution in gerontology and geriatrics should be placing more emphasis on precision, personalized interventions. Here, we have outlined general approaches to the prevention and treatment of age-associated frailty. These must be tailored to the specific needs and characteristics of each individual.
Related Concept Videos
Lifestyle Factors and Health
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Heart Failure VII: Nursing Interventions
Heart Failure VI: Adjunct Therapies
COPD: Management Using Bronchodilators and Corticosteroids
Atherosclerosis III: Management
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...

