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Related Concept Videos

Viruses of Archaea01:29

Viruses of Archaea

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Archaeal viruses play a crucial role in the ecosystems of extremophilic archaea, particularly those belonging to the phyla Euryarchaeota and Crenarchaeota. By shaping host evolution and facilitating gene transfer, these viruses influence microbial communities and contribute to genetic diversity in extreme environments. The archaea they infect thrive in acidic hot springs and hydrothermal vents characterized by high temperatures and low pH. Archaeal viruses exhibit remarkable structural...
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Surface Appendages of Archaea01:23

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Archaeal surface appendages are highly specialized structures essential for environmental adaptation, encompassing roles in adhesion, biofilm formation, and motility. Among these appendages, pili and archaella stand out for their distinct morphologies and functionalities, enabling archaea to thrive in diverse and often extreme environments.Pili: Adhesion and Biofilm FormationPili are filamentous structures assembled from pilin protein subunits, primarily contributing to adhesion and biofilm...
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Ribosomal RNA Synthesis02:53

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Ribosome synthesis is a highly complex and coordinated process involving more than 200 assembly factors. The synthesis and processing of ribosomal components occurs not only in the nucleolus but also in the nucleoplasm and the cytoplasm of eukaryotic cells.
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Diversity of Archaea III01:27

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Crenarchaeota, a prominent phylum of Archaea, is remarkable for its ability to thrive in extreme environments characterized by high temperatures and acidity. These microorganisms inhabit sulfuric hot springs, volcanic systems, and submarine hydrothermal vents, where temperatures often exceed 100°C. The unique adaptations of Crenarchaeota not only allow survival under such extreme conditions but also provide insights into the mechanisms of life in primordial Earth-like...
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Nucleoid01:24

Nucleoid

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The nucleoid represents a structurally and functionally distinct region within prokaryotic cells, where the cell's DNA and associated proteins are housed. Unlike eukaryotic cells, prokaryotes lack a membrane-bound nucleus, and the nucleoid facilitates the organization and accessibility of the genetic material within this constraint. The DNA in most bacteria and archaea exists as a single, circular, double-stranded molecule that is highly compacted through supercoiling and interactions with...
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Eukaryotic RNA Polymerases00:58

Eukaryotic RNA Polymerases

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RNA Polymerase (RNAP) is conserved in all animals, with bacterial, archaeal, and eukaryotic RNAPs sharing significant sequence, structural, and functional similarities. Among the three eukaryotic RNAPs, RNA Polymerase II is most similar to bacterial RNAP in terms of both structural organization and folding topologies of the enzyme subunits. However, these similarities are not reflected in their mechanism of action.
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Updated: Sep 9, 2025

Identification of Circular RNAs using RNA Sequencing
08:25

Identification of Circular RNAs using RNA Sequencing

Published on: November 14, 2019

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Circular RNAs in Archaea.

Hubert F Becker1,2, Sébastien Ferreira-Cerca3

  • 1Laboratoire d'Optique et Biosciences (CNRS UMR7645, INSERM U1182), École Polytechnique, Institut polytechnique de Paris, Palaiseau, France. hubert.becker@polytechnique.edu.

Advances in Experimental Medicine and Biology
|August 31, 2025
PubMed
Summary
This summary is machine-generated.

Circular RNAs, though known for decades, are newly explored in archaea. This chapter reviews their biology, focusing on circular pre-ribosomal RNAs and Box C/D RNAs in archaeal species.

Keywords:
ArchaeaBox C/D RNACircular RNARNA ligaserRNAsnoRNA

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Area of Science:

  • Molecular Biology
  • Genomics
  • Archaea Research

Background:

  • Circular RNAs (circRNAs) have been known for over 40 years.
  • Recent research has uncovered their wide phylogenetic distribution.
  • Most studies have focused on eukaryotic circRNAs, leaving archaeal circRNAs understudied.

Purpose of the Study:

  • To provide an overview of circular RNA discovery in archaea.
  • To summarize current knowledge on archaeal circular RNA biology.
  • To highlight specific examples like circular pre-ribosomal RNAs and Box C/D RNAs.

Main Methods:

  • Literature review and synthesis of existing studies on archaeal circRNAs.
  • Analysis of reported molecular mechanisms and functions.
  • Focus on specific archaeal RNA types.

Main Results:

  • Circular RNAs have been identified across diverse archaeal lineages.
  • Key examples include circular pre-ribosomal RNAs and Box C/D RNAs.
  • Understanding of their biological roles in archaea is still developing.

Conclusions:

  • Circular RNAs represent a conserved molecular feature in archaea.
  • Further research is needed to fully elucidate their functions and mechanisms in archaeal biology.
  • This chapter serves as a foundational resource for archaeal circRNA studies.