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Updated: Sep 9, 2025
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Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
Published on: March 29, 2022
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Beyond Refractive Error: Myopia's Exponential Burden on Retinal Health with Each Diopter.
Leo Arnal1, Yeabsira Mesfin2, Christine Xu1
1Byers Eye Institute, Stanford University School of Medicine.
Research Square
|September 2, 2025
Summary
Myopia significantly increases the risk of serious retinal diseases, with risk escalating with greater myopia severity. Early detection and monitoring are crucial for patients with high myopia to prevent vision loss.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Myopia Research
Background:
- Myopia is a global epidemic with increasing urgency regarding its link to vision-threatening retinal complications.
- Understanding the association between myopia severity and retinal diseases is critical for public health.
Purpose of the Study:
- To quantify the burden of myopia by examining its association with key retinal diseases.
- To determine how the risk of retinal complications escalates with increasing myopia severity.
Main Methods:
- Retrospective cohort study utilizing the STARR clinical data warehouse.
- Myopia severity defined by spherical equivalent and axial length (non-myopic, myopic, highly myopic, severely myopic).
- Primary outcomes included choroidal neovascularization (CNV), myopic macular degeneration (MMD), foveoschisis, macular hole (MH), rhegmatogenous retinal detachment (RRD), and foveal retinal detachment (FRD).
Main Results:
- Retinal complications occurred at younger ages with increasing myopia severity.
- Compared to non-myopes, severely myopic patients had 8.15 times higher odds of developing any retinal complication.
- Odds of specific complications increased per diopter of myopia, with markedly elevated odds for severe myopes (e.g., MMD OR 60.19).
Conclusions:
- Myopia is independently associated with higher odds of retinal diseases.
- A dose-response relationship exists, where risk increases incrementally with myopia severity.
- Highlights the importance of early risk stratification, tailored monitoring, and timely referral for high and severe myopia patients.
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