Reliability and Construct Validity of Patient-Reported Outcome Measurement Information System Physical Function in...

Area of Science:

• Vascular Medicine
• Health Outcomes Research
• Psychometrics

Background:

• The construct validity of the Patient-Reported Outcome Measurement Information System physical function (PROMIS-PF) instrument in peripheral artery disease (PAD) populations is not well-established.
• This study aimed to evaluate the reliability and construct validity of the PROMIS-PF instrument in patients with PAD.

Purpose of the Study:

• To assess the test-retest reliability of the PROMIS-PF instrument.
• To determine the convergent and discriminant validity of the PROMIS-PF by comparing it with PAD-specific and general health measures.

Main Methods:

• Patients with PAD completed PROMIS-PF, SF-36, VascuQoL, WIQ, and PROMIS-depression instruments at two time points.
• Intraclass correlation coefficients were used to assess test-retest reliability.
• Spearman rank correlations were employed to evaluate convergent and discriminant validity.

Main Results:

• The PROMIS-PF demonstrated high reliability (0.96).
• PROMIS-PF showed strong correlations with PAD-specific measures like the WIQ (rho=0.86) and VascuQoL (rho=0.85).
• The instrument exhibited discriminant validity, with a low correlation to the SF-36 emotional wellbeing component (rho=0.15).

Conclusions:

• The PROMIS-PF is a reliable and valid measure for assessing physical function in patients with PAD.
• Its strong correlations with PAD-specific measures and discriminant validity support its clinical utility.
• Findings support the use of PROMIS-PF in PAD clinical research and patient care.