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Updated: Jan 17, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
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Non-covalent interaction-controlled site-selective benzylic C(sp3)-H oxidation

Reina Nonami1, Honoka Toyama1, Kanata Shiraishi1

  • 1Department of Interdisciplinary Engineering Sciences, Interdisciplinary Graduate School of Engineering Sciences, Kyushu University, 6-1 Kasugakoen, Kasuga-shi, Fukuoka 816-8580, Japan.

Chemical Communications (Cambridge, England)
|September 15, 2025
PubMed
Summary

This study introduces a novel catalyst for selective benzylic C(sp3)-H oxidation. The method precisely targets the meta-position, even with multiple reaction sites or competing reactions.

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