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Updated: Aug 3, 2026

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
Published on: October 2, 2015
Lead-Tutor: An Open-Access Educational Resource for Deep Brain Stimulation Electrode Localizations
Savir Madan1, Lauren A Hart1, Ningfei Li2
1Center for Brain Circuit Therapeutics, Department of Neurology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Abstract:
Deep Brain Stimulation (DBS) is a neurosurgical procedure that involves implanting electrodes into specific brain regions to treat brain disorders. Accurate reconstruction of electrode placement is crucial for treatment optimization. Several systems, such as Lead-DBS, have been developed to reconstruct DBS electrodes, and typically require expert user input. However, open DBS datasets with localized electrodes are not available, posing a challenge to train research personnel on accurate use of these methods. In this paper, we introduce Lead-Tutor, an open-access educational resource that combines an imaging dataset of anonymized DBS cases with a software tool for self-teaching. This resource includes a dataset of pre- and post-operative magnetic resonance imaging (MRI) and computed tomography (CT) scans from ten patients with DBS implants. Along with this dataset, we provide a means for users to practice and enhance their electrode localization skills through the Lead-DBS pipeline. Aimed at new scientists in the DBS field, Lead-Tutor is a comprehensive resource available within Lead-DBS that promotes open science and education for enhanced reproducibility and potential clinical applications.
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