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Fusobacterium on the Rise: A Decade of Otogenic and Beyond

Sraya Kraus1,2, Goni Peleg1,2, Maayan Shachor1,2

  • 1From the Department of Pediatrics C, Schneider Children's Medical Center of Israel, Petach Tikva.

The Pediatric Infectious Disease Journal
|September 18, 2025
PubMed

Insights

Pediatric Fusobacterium infections are increasing, often affecting the ear but also other body systems. These complex infections require awareness for effective diagnosis and management.

Area of Science:

  • Pediatric Infectious Diseases
  • Microbiology
  • Epidemiology

Background:

  • Fusobacterium is an emerging pediatric pathogen causing diverse infections.
  • Large-scale studies on pediatric Fusobacterium infections are limited.

Purpose of the Study:

  • To assess the incidence, clinical features, complications, and outcomes of pediatric Fusobacterium infections.
  • To analyze trends in pediatric Fusobacterium infections over a 13-year period.

Main Methods:

  • Retrospective cohort study of children aged 0-18 years.
  • Data collected from a tertiary pediatric hospital between 2010 and 2023.
  • Statistical analysis including linear regression to identify trends.

Main Results:

  • A 10-fold increase in Fusobacterium infection incidence observed over 13 years.
  • Otogenic infections were most common (50.2%), followed by skin/soft tissue, intra-abdominal, and pharyngeal.
  • Significant rise in Fusobacterium isolations affecting both otologic and non-otologic sites.

Conclusions:

  • Pediatric Fusobacterium infections are rising and present with significant complexity and complications.
  • Infections are predominantly otogenic but involve multiple body systems.
  • Understanding the evolving epidemiology is crucial for optimizing diagnosis and management.
Abstract

Keywords:
complicationsincidenceotogenic

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