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Published on: June 10, 2025
Contemporary Baseline Clinical Profile of Chronic Hypertensive Heart Failure in Ibadan, Nigeria
O S Ogah1,2, O A Orimolade1, A A Adebiyi1,2
1Cardiology Unit, Department of Medicine, University College Hospital, Ibadan, Ibadan, Oyo State, Nigeria.
Insights
Hypertensive heart disease in Nigeria affects a younger population than in high-income countries. Early hypertension prevention is crucial to reduce cardiovascular disease burden in Sub-Saharan Africa.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Cardiovascular disease (CVD) is a leading cause of death in Sub-Saharan Africa (SSA).
- Data on hypertensive heart disease patterns in SSA is limited.
- Hypertensive heart disease poses a significant health challenge in the region.
Purpose of the Study:
- To describe the characteristics of heart failure due to hypertensive heart disease in Ibadan, Nigeria.
- To provide insights into the demographics and clinical features of this condition in the Nigerian population.
Main Methods:
- A hospital-based cross-sectional study was conducted at the University College Hospital, Ibadan, Nigeria.
- Data was collected from 753 patients with chronic hypertensive heart failure between August 2016 and July 2021.
- Statistical analysis was performed using SPSS, with a significance level of p < 0.05.
Main Results:
- The study included 753 subjects with a mean age of 60.3 years.
- Diabetes mellitus was the most common comorbidity (13.9%).
- Females had higher serum sodium, creatinine, and total cholesterol. Males were more prone to left-axis deviation, left atrial abnormality, and heart failure with reduced ejection fraction.
Conclusions:
- Hypertensive heart failure in Ibadan affects a younger demographic compared to high-income countries.
- Findings align with existing data from other SSA regions.
- Emphasizes the need for widespread hypertension preventive programs to mitigate cardiovascular disease.
Introduction:
Cardiovascular disease (CVD) has become the major cause of morbidity and mortality in Sub-Saharan Africa (SSA). Despite this, there is still very little data on the pattern of hypertensive heart disease in SSA.
Objective:
This study described the characteristics of heart failure caused by hypertensive heart disease in Ibadan, Nigeria.
Methods:
This was a hospital-based cross-sectional study conducted in the cardiology unit of the Department of Medicine, University College Hospital, Ibadan, Nigeria. Eligible patients were those presenting with chronic hypertensive heart failure to the cardiology unit or referred to the unit for the same purpose. Data collection started from August 1, 2016, to July 31, 2021. Analysis was done with the SPSS statistical package. A 2-tailed p-value of <0.05 was assumed to be statistically significant.
Results:
A total of 753 subjects met the inclusion criteria for the study. The mean age of the population was 60.3 (range, 18-98 years). The most common co-morbidity was diabetes mellitus (13.9%). About 54% of the subjects had a previous history of heart failure. Serum sodium (p = 0.022), creatinine (p = 0.001), and total cholesterol (p = 0.004) were significantly higher in females. Men are more likely to have left-axis deviation (p=0.016) and left atrial abnormality (p=0.016). Heart failure with reduced ejection fraction was common in males.
Conclusion:
HHF in Ibadan, Nigeria, affects a relatively younger population compared to their counterparts in high-income countries. Our findings are similar to data from other parts of sub-Saharan Africa. Preventive programmes should be utilised at all levels to stem the menace of hypertension.
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