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Leveraging ChatGPT for Report Error Audit: An Accuracy-Driven and Cost-Efficient Solution for Ophthalmic Imaging
Yufeng Xu1,2, Daohuan Kang3, Danli Shi4,5
1Eye Center of Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Ophthalmology and Therapy
|September 30, 2025
Summary
ChatGPT-4o effectively audits ophthalmic imaging reports, comparable to human specialists. This AI integration significantly reduces review time and costs for fundus fluorescein angiography and ocular B-scan ultrasound reports.
Area of Science:
- Ophthalmology
- Artificial Intelligence
- Medical Imaging Analysis
Background:
- Accurate ophthalmic imaging reports (FFA, B-scan ultrasound) are critical for clinical decisions.
- Current reporting workflows involving residents, technicians, and ophthalmologists are time-consuming and error-prone.
- Evaluating AI's role in auditing these reports is crucial for workflow optimization.
Purpose of the Study:
- To assess ChatGPT-4o's effectiveness in auditing errors in fundus fluorescein angiography (FFA) and ocular B-scan ultrasound reports.
- To evaluate the potential of ChatGPT-4o to reduce time and costs in ophthalmic reporting.
- To compare AI's error detection accuracy against human reviewers.
Main Methods:
- GPT-4o analyzed 100 FFA and 80 ocular B-scan reports for errors like incorrect eye laterality and anatomical descriptions.
- GPT-4o's accuracy was benchmarked against retinal specialists, general ophthalmologists, and ophthalmic technicians.
- Cost-effectiveness analysis and a real-world validation with 20 erroneous reports were conducted.
Main Results:
- GPT-4o achieved a 79.0% error detection rate, comparable to general ophthalmologists (78.0%).
- AI integration reduced report review time by 86% (0.27h vs. 2.17-3.19h) and costs from $0.21 to $0.03 per report.
- In real-world tests, GPT-4o detected 18/20 errors with no false positives.
Conclusions:
- ChatGPT-4o effectively audits ophthalmic imaging reports, identifying common errors.
- Implementing AI can alleviate ophthalmologist workload, streamline reporting, and cut costs.
- This technology has the potential to improve clinical workflow and patient outcomes.

