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MTA-Fillapex sealer penetration following activation with various irrigation protocols: a scanning electron
Hossein Saghebi1, Parisa Ranjbarian2, Amir Mansour Shirani3
1Dental school, Islamic Azad University Isfahan (Khorasgan) Branch, Isfahan, Islamic Republic of Iran.
Lasers in Medical Science
|October 8, 2025
Summary
980 nm laser activation significantly enhanced MTA-fillapex sealer penetration into dentinal tubules compared to other methods. This irrigation protocol shows potential for improved root canal sealing, particularly in the apical third.
Area of Science:
- Endodontics
- Dental Materials Science
Background:
- MTA-fillapex is a widely used root canal sealer.
- Effective sealing of dentinal tubules is crucial for endodontic treatment success.
- The influence of irrigation activation methods on sealer penetration requires further investigation.
Purpose of the Study:
- To compare the penetration depth of MTA-fillapex sealer into dentinal tubules.
- To evaluate the efficacy of different irrigation activation procedures on sealer penetration.
Main Methods:
- This in-vitro study utilized 40 mandibular premolars, divided into four groups: control, ultrasonic activation, XP-Endo Finisher, and 980-diode laser activation.
- Teeth were obturated with MTA-fillapex using a single-cone technique.
- Sealer penetration was assessed using scanning electron microscopy at 2, 5, and 8 mm from the apex.
Main Results:
- 980 nm laser activation resulted in significantly higher MTA-fillapex sealer penetration (p < 0.001).
- No significant difference in penetration was observed between ultrasonic and XP-Endo Finisher at 2 and 5 mm depths (p > 0.05).
- XP-Endo Finisher showed significantly greater penetration than ultrasonic activation at 8 mm (p > 0.001). Penetration increased significantly with depth from apex (p < 0.001).
Conclusions:
- Irrigation activation protocols significantly impact MTA-fillapex sealer penetration.
- 980 nm laser irrigation demonstrates potential for superior sealing ability in the apical third of root canals.

