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Apical Surgery of a Maxillary Left Central Tooth Using NeoPutty After Retreatment Failure: A Case Report
Sajedeh Namaei Ghasemi1, Zakieh Kheradmand2, Siavash Moushekhian1
1Endodontics Department, Faculty of Dentistry Mashhad University of Medical Sciences Mashhad Iran.
Clinical Case Reports
|October 13, 2025
Summary
This study details a successful apical surgery using NeoPutty, a novel bioceramic material, to treat a persistent infection and bone perforations in a maxillary central incisor. The findings highlight NeoPutty
Area of Science:
- Endodontics and Dental Materials Science
- Regenerative Endodontics
- Biomaterials in Dentistry
Background:
- Persistent infections after endodontic retreatment pose significant clinical challenges.
- Bone perforations, particularly in anterior teeth, complicate treatment outcomes.
- Novel biomaterials are needed for effective management of complex endodontic cases.
Purpose of the Study:
- To report the first-time use of NeoPutty as a root-end filling material in apical surgery.
- To evaluate the efficacy of NeoPutty in treating persistent apical periodontitis with bone perforations.
- To assess the biocompatibility and antibacterial properties of NeoPutty in a clinical setting.
Main Methods:
- Apical surgery was performed on a maxillary central incisor with persistent infection and labial/palatal bone perforations.
- NeoPutty, a premixed bioceramic putty (tricalcium and dicalcium silicate), was used for root-end filling.
- Clinical and radiographic assessments were conducted post-operatively.
Main Results:
- Successful apical surgery outcome was achieved.
- NeoPutty demonstrated favorable handling and placement characteristics.
- The material contributed to the resolution of the infection and healing of bone perforations.
Conclusions:
- NeoPutty is a viable and effective material for root-end filling in apical surgery.
- Its use in this case suggests potential for managing complex endodontic infections and perforations.
- Further research is warranted to explore NeoPutty's long-term efficacy and applications in endodontics.

