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Using Eye-tracking to Assess the Relative Importance of Visual and Vestibular Input to Subcortical Motion Processing in the Roll Plane
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Visual Snow Is Susceptible to the Motion Aftereffect.

Samantha A Montoya1, Anna J Hillstrom2, Karly D Allison2

  • 1University of Minnesota Twin Cities, Neuroscience Minneapolis, Minnesota, United States.

Investigative Ophthalmology & Visual Science
|October 14, 2025
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Summary
This summary is machine-generated.

Visual snow, a condition of flickering specks, is affected by motion aftereffects, suggesting it originates in early visual pathways. This finding may lead to new treatments for visual snow syndrome.

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Area of Science:

  • Neuroscience
  • Visual Perception
  • Ophthalmology

Background:

  • Visual snow syndrome (VSS) is characterized by persistent visual static.
  • The underlying neural mechanisms of VSS remain largely unknown.
  • Current treatments for VSS are limited.

Purpose of the Study:

  • To investigate if spontaneous neural activity causing visual snow reaches motion-selective areas.
  • To test the hypothesis that visual snow originates early in the visual pathway.
  • To utilize the motion aftereffect (MAE) to probe VSS neural mechanisms.

Main Methods:

  • Eleven participants with VSS and 12 controls adapted to moving gratings.
  • Participants reported the perceived motion of their visual snow after adaptation.
  • The duration of adapting stimuli was varied to assess MAE strength.

Main Results:

  • Most VSS participants (10/11) perceived their visual snow moving in the opposite direction of adapting stimuli.
  • The duration of the motion aftereffect showed a linear relationship with adapter duration on a log-log axis.
  • Participants with VSS exhibited a typical MAE to external visual stimuli in control conditions.

Conclusions:

  • Visual snow is influenced by the motion aftereffect, indicating it involves motion-selective neurons, potentially including area V5/MT.
  • The findings suggest that neural activity generating visual snow propagates through the visual system.
  • Identifying the neural origins of visual snow could pave the way for targeted therapeutic interventions.