Case Series of Deep-Seated Pyogenic Granulomas in Pediatric Patients

Deep-seated pyogenic granulomas (DSPG) are a rare variant of pyogenic granulomas and are commonly mistaken for other entities. Often, DSPG present as blue papulonodules without ulceration, and their clinical and histologic appearance can mimic other common subcutaneous nodules seen in pediatric patients, including hemangiomas, venous malformations, pilomatricomas, and kaposiform hemangioendotheliomas. Herein, we describe the clinical and histologic features of six pediatric cases of DSPG, as the clinicopathologic correlation of DSPG is scarce in the literature, especially in pediatric patients.