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Updated: Jan 15, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates
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Biliary Atresia Splenic Malformation: A Case Study.

Joanna Hirsch1, Amy J Jnah2

  • 1Department of Advanced Practice Nursing Practice and Education, East Carolina University College of Nursing, Greenville, NC, USA hirschj22@students.ecu.edu joanna.hirsch92@gmail.com.

Neonatal Network : NN
|October 15, 2025
PubMed
Summary
This summary is machine-generated.

Biliary atresia splenic malformation (BASM) is a rare condition in infants. This case report details its diagnosis and management, offering insights for neonatal providers.

Keywords:
atrioventricular canal defect (AVCD)biliary atresia splenic malformation (BASM)heterotaxymalrotationneonatepartial anomalous pulmonary venous returnpolyspleniasitus inversus

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Area of Science:

  • Pediatric Gastroenterology
  • Neonatal Surgery
  • Hepatology

Background:

  • Biliary atresia (BA) is a progressive inflammatory biliary tree disease causing cholestatic jaundice, cirrhosis, and liver failure.
  • BA is the leading cause of chronic liver disease and pediatric liver transplants.
  • BA can co-occur with laterality defects, forming biliary atresia splenic malformation (BASM), which constitutes 10% of BA cases.

Purpose of the Study:

  • To present a case report of a neonate diagnosed with BASM.
  • To discuss risk factors, clinical manifestations, diagnostic approaches, and management strategies for BASM.
  • To provide insights into long-term implications and care strategies for optimizing outcomes in families affected by BASM.

Main Methods:

  • Case report presentation of a neonate with BASM.
  • Review of literature on risk factors, clinical features, diagnostics, and management of BASM.
  • Discussion of the Kasai portoenterostomy procedure and long-term care.

Main Results:

  • The article details a specific case of neonatal BASM.
  • It outlines current understanding and approaches to managing this rare condition.
  • It emphasizes the importance of early diagnosis and intervention.

Conclusions:

  • BASM requires prompt recognition and management to improve patient outcomes.
  • Comprehensive care strategies are essential for affected infants and their families.
  • Neonatal providers benefit from understanding the nuances of BASM diagnosis and treatment.