Orthobiologic Use in Ligament Reconstruction and Repair

Ligament injuries are a common type of musculoskeletal condition, with an estimated 17 million occurring annually in the United States, resulting in an economic burden exceeding US$40 billion. The growing demand for faster recovery and better surgical outcomes has led to increased interest in orthobiologics. However, the wide variability in ligament healing, surgical techniques, biological factors, and preparation methods makes it challenging to generalize research results. More studies are needed to fully understand the impact of current orthobiologics on ligament healing. Although current research in ligament repair and reconstruction enhanced with orthobiologics shows promise, it is still not fully evidence-based.