Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

Antiasthma Drugs: β2-Adrenoceptor Agonists

1.6K
Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce...
1.6K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.2K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.2K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.1K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.1K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

1.7K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
1.7K
Antiasthma Drugs: Methylxanthines01:24

Antiasthma Drugs: Methylxanthines

1.6K
Theophylline, a member of the methylxanthine class of bronchodilators, has long been used in asthma management. While its exact mechanism of action is not fully understood, it is believed to have multiple effects on various cellular processes.
Theophylline is thought to inhibit phosphodiesterase enzymes, increasing intracellular levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). This rise in cAMP and cGMP concentrations stimulates cardiac function,...
1.6K
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.4K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Emergency department management of dehydration in pediatric patients.

Pediatric emergency medicine practice·2025
Same author

The Management of Children and Youth With Pediatric Mental and Behavioral Health Emergencies.

Annals of emergency medicine·2023
Same author

Six Diagnoses of Separation: Impact of COVID-19 on Pediatric Emergency Department Visits: A Multicenter Study.

The Journal of emergency medicine·2022
Same author

Optimizing the workforce: a proposal to improve regionalization of care and emergency preparedness by broader integration of pediatric emergency physicians certified by the American Board of Pediatrics.

Journal of the American College of Emergency Physicians open·2021
Same author

Injectable dexamethasone sodium phosphate administered orally? A pharmacokinetic analysis of a common emergency department practice.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG·2015
Same author

Cutaneous methicillin-resistant Staphylococcus aureus in a suburban community hospital pediatric emergency department.

The Journal of emergency medicine·2009
Same journal

Acute Otitis Media-Watch and Wait Is Not a Myth.

Emergency medicine clinics of North America·2026
Same journal

Hot or Not? Myths and Misconceptions About Antipyretics for Pediatric Fever.

Emergency medicine clinics of North America·2026
Same journal

Epinephrine Improves Outcomes in Out-Of-Hospital Cardiac Arrests.

Emergency medicine clinics of North America·2026
Same journal

Myth: Pretreatment Prevents Intravenous Contrast Reactions in the Emergency Department.

Emergency medicine clinics of North America·2026
Same journal

Ketamine Use in Acute Brain Injury: Debunking the Myth.

Emergency medicine clinics of North America·2026
Same journal

Cephalosporins Should be Avoided in Patients with Penicillin Allergy.

Emergency medicine clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Jan 14, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.4K

Asthma-Beyond Albuterol.

Christopher S Amato1, Mahsa Akhavan-Pajoohi1

  • 1Departments of Emergency Medicine & Pediatrics, Sydney Kimmel Medical College at Jefferson University, Philadelphia, USA.

Emergency Medicine Clinics of North America
|October 17, 2025
PubMed
Summary
This summary is machine-generated.

Pediatric asthma remains a significant health concern. This review identifies evidence-based treatments to improve outcomes for children with asthma.

Keywords:
AlbuterolAsthmaReactive airway diseaseRespiratory distress

More Related Videos

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice
09:58

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice

Published on: April 13, 2010

23.3K
Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

41.2K

Related Experiment Videos

Last Updated: Jan 14, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.4K
A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice
09:58

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice

Published on: April 13, 2010

23.3K
Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

41.2K

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Clinical Pediatrics

Background:

  • Asthma is a prevalent chronic respiratory condition in children.
  • Despite advances in care, pediatric asthma significantly contributes to morbidity and mortality.
  • Effective management strategies are crucial for improving patient outcomes.

Purpose of the Study:

  • To review evidence-based literature on pediatric asthma treatments.
  • To identify therapeutic interventions that optimize patient response.
  • To provide guidance for managing childhood asthma.

Main Methods:

  • Systematic review of evidence-based literature.
  • Analysis of treatment efficacy in pediatric asthma patients.
  • Synthesis of current research on asthma management.

Main Results:

  • Identification of key evidence-based treatment options for pediatric asthma.
  • Evaluation of treatment effectiveness based on scientific literature.
  • Summary of best practices for managing childhood respiratory disorders.

Conclusions:

  • Optimized treatment selection is vital for improving pediatric asthma outcomes.
  • Evidence-based interventions can mitigate asthma's impact on children.
  • Continued research and application of findings are essential for advancing pediatric respiratory care.