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Diabetic Retinopathy Screening Among Federally Qualified Health Center Patients Using Point-of-Care AI: DRES-POCAI: A
Edgar A Diaz1, Marva L Seifert2, Vida Gruning1
1San Ysidro Health, San Diego, California.
JAMA Network Open
|October 21, 2025
Summary
This study evaluates an AI-powered diabetic retinopathy screening (DRS) system integrated into federally qualified health centers (FQHCs) to improve screening rates and early detection for underserved populations.
Area of Science:
- Ophthalmology
- Artificial Intelligence in Healthcare
- Public Health
Background:
- Diabetic retinopathy screening (DRS) rates are historically low in underserved populations due to access barriers.
- Artificial intelligence (AI) offers a potential solution to improve screening accessibility and outcomes.
- Federally Qualified Health Centers (FQHCs) are crucial for delivering care to underserved communities.
Purpose of the Study:
- To increase DRS rates within FQHC primary care workflows.
- To facilitate early detection of diabetic retinopathy (DR) and improve timely specialist follow-up.
- To assess the impact of AI-powered DRS on patient knowledge, attitudes, and satisfaction.
Main Methods:
- A randomized clinical trial involving 848 diabetic patients aged 22+ at two FQHC sites.
- The intervention group received AI-powered DRS integrated with electronic health records (EHRs).
- The control group received standard referral care to eye specialists.
Main Results:
- The primary outcome is DRS completion status.
- Secondary outcomes include DR diagnosis stage, referral completion, and patient-reported outcomes related to AI-powered DRS.
- Study results are pending publication following data collection and analysis.
Conclusions:
- The DRES-POCAI trial will determine the effectiveness of AI-powered DRS in FQHC settings.
- This AI integration aims to enhance screening rates and facilitate early DR diagnosis and treatment.
- Findings are expected to inform the optimal implementation of AI-driven eye care in primary care.

