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Updated: Jan 14, 2026

Author Spotlight: Advancing Thrombolytic Testing by Integrating Flow Dynamics in In Vitro Models
Published on: April 19, 2024
Cold plasma process ensnares fibrin-rich clots in an adhesive web
Jesse George Atherton Jones1,2, Lakshmi Nair3, Vinoy Thomas3
1Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA.
None:
Advances in mechanical thrombectomy (MT) devices have reduced mortality and improved the quality of life among stroke patients. Favorable (mRS 0-2 at 90 days) post-procedure outcomes depend heavily upon the degree of recanalization. Fibrin-rich thrombi pose a major impediment to adequate (TICI 2B) clot retrieval, as their firm composition resists extraction. We describe a low-temperature plasma process for modifying stent retrievers with fibrinogen. Fibrinogen binding translates into greater efficacy in capturing fibrin-rich clots in vitro. This advance may improve MT outcomes through faster and more complete clot retrievals.
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