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Updated: Jan 12, 2026

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Published on: October 17, 2017
Headaches due to Low and High Intracranial Pressure
Melissa E Phuphanich1, Catherine Cho2, Kristen Clark2
1Interventional Pain Service, Department of Physical Medicine and Rehabilitation, VA Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Building 500, Mail Code 117, Los Angeles, CA 90073, USA; Division of Physical Medicine and Rehabilitation, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
This article details high-pressure and low-pressure headaches, covering causes, symptoms, and treatments. Early diagnosis and multidisciplinary care are key for managing these challenging headache syndromes.
Area of Science:
- Neurology
- Headache Medicine
Background:
- High-pressure headaches are often associated with idiopathic intracranial hypertension.
- Low-pressure headaches frequently result from cerebrospinal fluid leaks.
Purpose of the Study:
- To provide a comprehensive overview of high-pressure and low-pressure headaches.
- To discuss pathophysiology, clinical presentation, diagnosis, and management strategies.
Main Methods:
- Review of current literature on high-pressure and low-pressure headaches.
- Emphasis on diagnostic approaches including advanced imaging.
- Discussion of multidisciplinary management options.
Main Results:
- Idiopathic intracranial hypertension is a common cause of high-pressure headaches, particularly in young women.
- Cerebrospinal fluid leaks are a primary cause of low-pressure headaches, often leading to refractory symptoms.
- Timely diagnosis and intervention are crucial for preventing complications like vision loss.
Conclusions:
- Effective management of high-pressure and low-pressure headaches requires a multidisciplinary approach.
- Pharmacologic, procedural, and surgical options are available for treatment.
- Optimizing care for these headache syndromes improves patient outcomes and quality of life.
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