Assessing hemodynamic changes before and after pump in CABG surgery and its factors

One of the main complications after coronary artery bypass grafting (CABG) is postoperative clinical and para-clinical changes, which present a significant challenge.

This descriptive cross-sectional study included 109 patients who were candidates for CABG and were admitted to the surgical intensive care unit at Tehran Heart Center Hospital, selected using random sampling and a checklist. Relationships between variables were analyzed with the Kolmogorov-Smirnov (K-S) test, paired t-test, and regression.

The findings from the mean changes before and after the pump showed that blood sugar (28.23 ± 33.43), lactate (6.59 ± 5.63), potassium (0.75 ± 0.47), and heart rate (12.36 ± 15.46) increased significantly after the pump compared to before the pump (p < 0.05), while hemoglobin (-2.5 ± 1.28), hematocrit (-6.61 ± 3.44), pH (-0.03 ± 0.06), PaO₂ (-92.95 ± 94.01), bicarbonate (-1.83 ± 2.38), and mean blood pressure (-2.25 ± 13.01) decreased significantly (p < 0.05). Gender had a significant effect on cerebral oximetry values on both the right (β = 5.461, p = 0.002) and left (β = 4.835, p = 0.004) sides, hemoglobin (β = 0.644, p = 0.017), and hematocrit (β = 2.055, p = 0.004). In addition, patients' comorbidities also had a positive effect on PaO₂ (β = 11.340, p = 0.044).

The clinical and para-clinical status in patients undergoing CABG surgery changes after on-pump surgery. In addition, comorbidities of patients have a positive and significant effect on PaO₂, as well as gender, on cerebral oximetry, hemoglobin, and hematocrit values.