Two new polyacetylenes from Bidens parviflora

Area of Science:

• Phytochemistry
• Natural Product Chemistry
• Medicinal Plant Research

Background:

• Bidens parviflora (Willd.) is utilized in traditional Dai medicine.
• Polyacetylenic compounds are known for diverse biological activities.

Purpose of the Study:

• To isolate and characterize novel polyacetylenic compounds from Bidens parviflora.
• To contribute to the understanding of the chemical constituents of this ethnomedicinal plant.

Main Methods:

• Extraction of aerial parts of Bidens parviflora using dichloromethane.
• Separation and purification of compounds using chromatographic techniques.
• Structural elucidation via UV, IR, HR-ESI-MS, 1D/2D NMR, and specific optical rotation measurements.

Main Results:

• Two novel polyacetylenic compounds, (2R)-trideca-3E,5Z,11E-triene-7,9-diyne-1,2,13-triol (1) and (2R)-trideca-11E-ene-5,7,9-triyne-1,2,13-triol (2), were identified.
• Comprehensive spectroscopic data confirmed the chemical structures of the isolated compounds.

Conclusions:

• The study successfully identified two new polyacetylenic compounds from Bidens parviflora.
• This research expands the knowledge of phytochemistry in ethnomedicinal plants.