Safety of Thread Lifting With APTOS and Energy-Based Technologies Under Artificial Intelligence-Guided High-Frequency
Daniel Perfeito1, Renata Viana2, Elaine Marques3
1Plastic Surgery, Olsen Almeida Dermatology, São Paulo, BRA.
Cureus
|November 11, 2025
Summary
AI-guided ultrasound enhances the safety of poly-L-lactic acid (PLLA) and polycaprolactone (PCL) thread lifts for facial rejuvenation. Combining these threads with same-day energy devices proved safe, with low complication rates below 5%.
Area of Science:
- Aesthetic medicine and dermatological procedures.
- Medical device technology and imaging.
- Biomaterials science in cosmetic surgery.
Background:
- Poly-L-lactic acid (PLLA) and polycaprolactone (PCL) suspension threads are key for nonsurgical facial rejuvenation.
- Precise placement in the superficial musculoaponeurotic system (SMAS) is critical for safety and efficacy.
- AI-assisted high-frequency ultrasound offers potential for improved procedural accuracy.
Purpose of the Study:
- To assess the safety of APTOS PLLA/PCL threads placed using AI-guided ultrasound.
- To evaluate the safety of combining thread lifting with same-day energy-based treatments.
- To analyze outcomes in a real-world aesthetic practice setting.
Main Methods:
- Retrospective observational study of 246 patients undergoing facial thread lifting.
- Procedures utilized APTOS Excellence Visage sutures with real-time ultrasound guidance.
- A subset of patients received concurrent energy-based treatments (ultrasound, radiofrequency, CO₂ laser).
Main Results:
- Overall adverse event incidence was under 5%, with no serious complications.
- Minor events included transient pain (4.1%), ecchymosis (2.0%), hematomas (0.8%), and granulomas (1.6%).
- Ultrasound confirmed accurate SMAS placement; no infections or thread issues occurred.
Conclusions:
- AI-assisted ultrasound guidance ensures safe and precise placement of PLLA/PCL threads.
- Combining thread lifting with same-day energy modalities is safe and does not increase adverse events.
- This approach offers a favorable safety profile for facial rejuvenation procedures.
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