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Updated: Jan 10, 2026
Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device
Published on: May 2, 2025
Recent Advances in the Pathology of Pediatric Brain and Spinal Tumors
1Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, and Pathology Queensland, Royal Brisbane and Women's Hospital, Level 2, Block 7, Butterfield Street, Herston, Queensland 4029, Australia.
Abstract:
The last decade has seen major advances in our understanding of the biology of pediatric brain and spinal cord tumors and why they are fundamentally different from their adult counterparts. Many of these advances have been adapted into the latest WHO classification of tumors of the central nervous system. This article summarizes the major changes to the WHO classification in this area, highlighting the key histopathologic and molecular features of these new entities.
