Diffuse Pediatric High Grade Gliomas

Advances in molecular and genomic testing have not only discriminated pediatric from adult high grade gliomas but also distinguished new entities in this family, 3 of which are new to the classification. We have reviewed the published literature to date and present the characteristic and most common findings of each type on structural MR imaging, as well as advanced imaging, where available. Prognostic features, particularly in diffuse midline gliomasK27a have also been described, in addition to practice recommendations.