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Published on: August 23, 2016
Central Nervous System Embryonal Tumors
Murat Alp Oztek1, Jason N Wright1
1Department of Radiology, Seattle Children's Hospital, University of Washington, 4800 Sand Point Way NE, M/S MA.7.220, PO Box 5371, Seattle, WA 98105, USA.
Abstract:
Central nervous system (CNS) embryonal tumors are a subset of aggressive pediatric brain tumors, more frequently seen in infants and young children. They share an aggressive imaging appearance with frequent disseminated disease and guarded prognosis; however, patient age, tumor location, and imaging characteristics such as enhancement pattern and peritumoral edema can help with differential diagnosis. In this article, we have reviewed medulloblastoma, atypical teratoid rhabdoid tumor, embryonal tumor with multilayered rosettes as well as newly recognized CNS neuroblastoma, FOXR2-activated and CNS tumor with BCOR internal tandem duplication.
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