Prostate Cancer Mortality Trend in Montenegro 1990-2018

Area of Science:

• Oncology
• Epidemiology
• Public Health

Background:

• Prostate cancer is a leading cause of cancer death globally, responsible for significant mortality in numerous countries.
• In 2020, prostate cancer caused an estimated 375,304 deaths worldwide, with a mortality rate of 7.7 per 100,000 men.
• It is the primary cause of cancer mortality in 48 countries, underscoring its global health impact.

Purpose of the Study:

• To analyze the prostate cancer mortality trends in Montenegro.
• To assess the changes in prostate cancer mortality rates between 1990 and 2018.
• To identify specific age groups most affected by prostate cancer mortality in Montenegro.

Main Methods:

• Utilized regression techniques, including joinpoint, linear, and Poisson regression, for trend assessment.
• Collected and analyzed prostate cancer mortality data for Montenegro spanning from 1990 to 2018.
• Applied age-standardization to the World Standard Population for accurate trend estimation.

Main Results:

• A total of 1,184 prostate cancer deaths were recorded in Montenegro between 1990 and 2018.
• Prostate cancer mortality rates showed a statistically significant annual increase of 2.4% (AAPC=2.4%, P<0.001).
• Mortality rates increased significantly in men aged 75-84 (2.7% annually, P<0.001) and non-significantly in men aged 65-74 (1.1% annually, P=0.452).

Conclusions:

• The observed increasing trend in prostate cancer mortality necessitates improved prevention, screening, and early diagnosis measures.
• Special attention should be directed towards older male populations, particularly those aged 75 and above.
• Effective treatment strategies must be enhanced to address the rising mortality rates in Montenegro.