Leveraging Systems-of-Systems Analysis to Strengthen Epidemic Intelligence for Preparedness and Response

John M Drake1, Justin Bahl1, Michael A Cacciatore1

  • 1John M. Drake, PhD, is a Professor, Odum School of Ecology; Justin Bahl, PhD, is a Professor Department of Epidemiology and Biostatistics and Department of Infectious Diseases; Michael A. Cacciatore, PhD, is an Associate Professor, Grady College of Journalism and Mass Communication; Glen Nowak, PhD, is a Professor, Department of Advertising and Public Relations; Éric Marty, PhD, is a Research Professional, Center for the Ecology of Infectious Diseases; Pejman Rohani, PhD, is a Professor, Odum School of Ecology and Department of Infectious Diseases; Sukanta Sarkar, PhD, is a Postdoctoral Associate, Odum School of Ecology; Guppy L. Stott, is a Graduate Student, Institute of Bioinformatics; and Amy K. Winter, PhD, is an Assistant Professor, Department of Epidemiology and Biostatistics: all at the University of Georgia, Athens, GA. Amin Ghadami, PhD, is a Research Assistant Professor of Civil and Environmental Engineering and Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, CA. Ellie Graeden, PhD, is a Research Professor, Center for Global Health Science and Security, Georgetown University, Washington, DC. Barbara A. Han, PhD, is a Disease Ecologist, Cary Institute of Ecosystem Studies, Millbrook, NY. Hailey Robertson, is a Graduate Student, Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT. Bogdan I. Epureanu, PhD, is a Professor, Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI.

Health Security
|December 10, 2025
PubMed
Abstract

Related Concept Videos

Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
468
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
440
Applications of GIS: Disaster Management and Emergency Response01:29

Applications of GIS: Disaster Management and Emergency Response

Geographic Information System (GIS) technology is essential for risk identification, action prioritization, and resource optimization in critical situations like flooding and earthquakes. By integrating spatial and demographic data, GIS provides a comprehensive framework for emergency response.GIS integrates data layers, like rainfall intensity, topography, elevation profiles, and river levels, to model high-risk flood zones. These layers assess areas susceptible to flooding based on their...
431
Statistical Methods for Analyzing Epidemiological Data01:25

Statistical Methods for Analyzing Epidemiological Data

Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
864
Integrated Healthcare System01:20

Integrated Healthcare System

An integrated healthcare system (IHS) is a set of organizations that provides for or arranges to provide coordinated and continuous service to a defined population. The IHS takes responsibility for that particular population's health status and outcome, both clinically and fiscally. An integrated healthcare system is a well-organized, well-coordinated, and collaborative network. The integrated delivery system is a network that connects different healthcare providers to deliver organized,...
2.3K
Causality in Epidemiology01:21

Causality in Epidemiology

Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.5K